BioSupercomputing Newsletter Vol.8

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4th Biosupercomputing Symposium Report

Computational Science Research Program, RIKEN
Eietsu Tamura

“Next-Generation Integrated Simulation of Living Matter (ISLiM)” has been comprehensively working on the Grand Challenge for Life Science, which is research and development of software in the field of life science targeting the “K computer” since the start of the project in October 2006. This project, which is organized by six research and development teams for Molecular Scale, Cell Scale, Organ and Body Scale, Brain and Neural Systems, Data Analysis Fusion, and High Performance Computing, will be completed at the end of the fiscal 2012.

At the final phase of the program, the “ISLiM International Symposium: 4th Biosupercomputing Symposium” was held from December 3 to 5, 2012, at Tokyo International Forum (Hall D) by inviting the following seven renowned overseas researchers in the field of modeling and simulations for expanding international visibility and collaborations:

 Pharmacueticals – Sandra R. B. Allerheiligen (Merck)
 Brain Science – Sten Grillner (Karolinska Institutet)
 Cell – Ion I. Moraru (University of Connecticut Health Center)
 Medicine – Grace Peng (National Institute of Health)
 Organ – Aleksander Popel (Johns Hopkins University)
 Molecules – Karissa Sanbonmatsu (Los Alamos NationalLaboratory)
 Molecules . Ruhong Zhou (IBM T.J. Watson Research Center)

Koji Kaya, Program Director, gave an opening speech, and two keynote speakers, seven invited speakers and 14 ISLiM speakers presented highlights on the research and development that have been conducted in this program.

There were 145 participants successfully joining the symposium.

The following are comments of some invited speakers from abroad.

During three days of symposiums, invited speakers and ISLiM team members communicated actively together. This was a good opportunity to present all the work of ISLiM and its results to major overseas researchers in the field, and gain their international visibilities.

The proceedings of this symposium is available in the Web site (URL:

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BioSupercomputing Newsletter Vol.8

Grand Challenge opens the way to the future of life science through innovative approach
Program Director, Computational Science Research Program, RIKEN
Koji Kaya
A Landmark Project that Brought on an Innovation in the Field of Life Scienc
Deputy-Program Director, Computational Science Research Program, RIKEN
Ryutaro Himeno
Report on Research
Multi-scale, multi-physics heart simulator UT-Hear
Graduate School of Frontier Sciences, the University of Tokyo
Toshiaki Hisada, Seiryo Sugiura, Takumi Washio,
Jun-ichi Okada, Akihito Takahashi
(Organ and Body Scale WG)
Simulation Model for Insulin Granule Kinetics in Pancreatic Beta Cells
Graduate School of System Informatics, Kobe University
Hisashi Tamaki(Cell Scale WG)
The road to brain-scale simulations on K
Brain Science Institute, RIKEN, Institute of
Neuroscience and Medicine (INM-6),
Juelich Research Center
Medical Faculty, RWTH Aachen University Markus Diesmann
(Brain and Neural Systems WG)
MD Core Program Development for Large-scale Parallelization
Computational Science Research Program, RIKEN
Yousuke Ohno(High-performance Computing Team)
Aiming to realize hierarchical integrated simulation in the circulatory organ system
and the musculoskeletal / cerebral nervous systems

Professor, Department of Mechanical Engineering and Department of Bioengineering The University of Tokyo
Shu Takagi(Theme3 GL)
Leading-edge large-scale sequence data analysis with K computer in order to promote the understanding of life programs and their diversity
Professor, Human Genome Center, The Institute of Medical Science, The University of Tokyo
Satoru Miyano(Theme4 GL)
4th Biosupercomputing Symposium Report
Computational Science Research Program, RIKEN
Eietsu Tamura
“K Computer” Compatible Computer: Installation of SCLS Computer System
HPCI Program for Computational Life Sciences, RIKEN
Yoshiyuki Kido
Event information and news